Lieberman, Michael, 1950-

Marks' basic medical biochemistry : a clinical approach / Basic medical biochemistry Michael Lieberman, PhD, Distinguished Teaching Professor, Department of Molecular Genetics, Biochemistry and Microbiology, University of Cincinnati College of Medicine, Cincinnati, Ohio, Alisa Peet, MD, Associate Dean Clinical Education, Associate Professor of Clinical Medicine, Lewis Katz School of Medicine at Temple University, Philadelphia, Pennsylvania ; illustrations by Matthew Chansky - Fifth edition - xii, 1051 pages : color illustrations ; 28 cm.

Includes bibliographical references and indexes

I: Fuel metabolism -- Metabolic fuels and dietary components -- The fed or absorptive state -- Fasting -- II: Chemical and biologic foundations of biochemistry -- Water, acids, bases, and buffers -- Structures of the major compounds of the body -- Amino acids in proteins -- Structure-function relationships in proteins -- Enzymes as catalysts -- Regulation of enzymes -- Relationship between cell biology and biochemistry -- Cell signaling by chemical messengers -- III: Gene expression and the synthesis of proteins -- Structure of the nucleic acids -- Synthesis of DNA -- Transcription: synthesis of RNA -- Translation: synthesis of proteins -- Regulation of gene expression -- Use of recombinant DNA techniques in medicine -- The molecular biology of cancer -- IV: Carbohydrate metabolism, fuel oxidation, and the generation of adenosine triphosphate -- Basic concepts in the regulation of fuel metabolism by insulin, glucagon, and other hormones -- Cellular bioenergetics: adenosine triphosphate and O2 -- Digestion, absorption, and transport of carbohydrates -- Generation of adenosine triphosphate from glucose, fructose, and galactose: glycolysis -- Tricarboxylic acid cycle -- Oxidative phosphorylation and mitochondrial function -- Oxygen toxicity and free-radical injury -- Formation and degradation of glycogen -- Pentose phosphate pathway and the synthesis of glycosides, lactose, glycoproteins, and glycolipids -- Gluconeogenesis and maintenance of blood glucose levels -- V: Lipid metabolism -- Digestion and transport of dietary lipids -- Oxidation of fatty acids and ketone bodies -- Synthesis of fatty acids, triacylglycerols, and the major membrane lipids -- Cholesterol absorption, synthesis, metabolism, and fate -- Metabolism of ethanol -- Integration of carbohydrate and lipid metabolism -- VI: Nitrogen metabolism -- Protein digestion and amino acid absorption -- Fate of amino acid nitrogen: urea cycle -- Synthesis and degradation of amino acids -- Tetrahydrofolate, vitamin B12, and S-adenosylmethionine -- Purine and pyrimidine metabolism -- Intertissue relationships in the metabolism of amino acids VII: tissue metabolism -- Actions of hormones that regulate fuel metabolism -- The biochemistry of erythrocytes and other blood cells -- Blood plasma proteins, coagulation, and fibrinolysis -- Liver metabolism -- Metabolism of muscle at rest and during exercise -- Metabolism of the nervous system -- The extracellular matrix and connective tissue

9781496324818 1496324811 9781496387721 1496387724

Clinical biochemistry