Kelley and Firestein's textbook of rheumatology / [edited by] Gary S. Firestein, Sherine E. Gabriel, Iain B. McInnes, James R. O'Dell.

Contributor(s): Firestein, Gary S [editor.] | Gabriel, Sherine E [editor.] | McInnes, Iain B [editor.] | O'Dell, James R [editor.]
Publisher: Philadelphia, PA : Elsevier, [2017]Copyright date: �2017Edition: Tenth editionDescription: 1 online resource : illustrations (some color)Content type: text | still image Media type: computer Carrier type: online resourceISBN: 9780323316965; 0323316964; 9780323414944; 032341494XOther title: Textbook of rheumatologyUniform titles: Kelley's textbook of rheumatology. 9th ed. �2013. Subject(s): Rheumatology | Rheumatism | Arthritis | Arthritis | Rheumatism | Rheumatology | Rheumatic Diseases | Joint Diseases | Collagen Diseases | Lupus Erythematosus, Systemic | Joint Diseases | Rheumatic Diseases | Collagen Diseases | Lupus Erythematosus, SystemicGenre/Form: Textbooks. | Electronic books. | Textbooks. | Electronic books. Additional physical formats: Print version:: Kelley and Firestein's textbook of rheumatology.DDC classification: 616.7/23 LOC classification: RC927Online resources: Click here for the e-copy
Contents:
Biology of the normal joint -- Synovium -- Cartilage and chondrocytes -- Biology, physiology, and morphology of bone -- Muscle : anatomy, physiology, and biochemistry -- Biomechanics -- Regenerative medicine and tissue engineering -- Proteinases and matrix degradation -- Dendritic cells : general overview and role in autoimmunity -- Mononuclear phagocytes -- Neutrophils -- T lymphocytes -- B cells -- Fibroblasts and fibroblast-like synoviocytes -- Mast cells -- Platelets -- Innate immunity -- Adaptive immunity and organization of lymphoid tissues -- Autoimmunity -- Metabolic regulation of immunity -- Genetics of rheumatic diseases -- Epigenetics of rheumatic diseases -- Complement system -- Prostaglandins, leukotrienes, and related compounds -- Cell recruitment and angiogenesis -- Cytokines -- Principles of signaling -- Immunologic repercussions of cell death -- Experimental models for rheumatoid arthritis -- Neuronal regulation of pain and inflammation -- Clinical research methods in rheumatic disease -- Economic burden of rheumatic diseases -- Assessment of health outcomes -- Biologic markers in clinical trials and clinical care -- Occupational and recreational musculoskeletal disorders -- Cardiovascular risk in inflammatory rheumatic disease -- Cancer risk in rheumatic diseases -- Introduction to physical medicine, physical therapy, and rehabilitation -- Pregnancy and rheumatic diseases -- History and physical examination of the musculoskeletal system -- Acute monoarthritis -- Evaluation and differential diagnosis of polyarthritis -- Skin and rheumatic diseases -- The eye and rheumatic diseases -- Neck pain -- Shoulder pain -- Low back pain -- Hip and knee pain -- Foot and ankle pain -- Hand and wrist pain -- Temporomandibular joint pain -- Fibromyalgia -- Synovial fluid analyses, synovial biopsy, and synovial pathology -- Arthrocentesis and injection of joints and soft tissue -- Anti-nuclear antibodies -- Autoantibodies in rheumatoid arthritis -- Acute phase reactants and the concept of inflammation -- Imaging in rheumatic diseases -- Biology and therapeutic targeting of prostanoids -- Glucocorticoid therapy -- Traditional dmards : methotrexate, leflunomide, sulfasalazine, hydroxychloroquine, and combination therapies -- Immunosuppressive drugs -- Anti-cytokine therapies -- Cell-targeted biologics and emerging targets : rituximab, abatacept, and other biologics -- Novel intra-cellular targeting agents in rheumatic disease -- Urate-lowering therapy -- Analgesic agents in rheumatic disease -- Nutrition and rheumatic diseases -- Etiology and pathogenesis of rheumatoid arthritis -- Clinical features of rheumatoid arthritis -- Treatment of rheumatoid arthritis -- Early synovitis and early undifferentiated arthritis -- Sj�ogren's syndrome -- Etiology and pathogenesis of spondyloarthritis -- Ankylosing spondylitis -- Undifferentiated spondyloarthritis -- Psoriatic arthritis -- Enteropathic arthritis -- Etiology and pathogenesis of systemic lupus erythematosus -- Clinical features of systemic lupus erythematosus -- Treatment of systemic lupus erythematosus --
Anti-phospholipid syndrome -- Etiology and pathogenesis of scleroderma -- Clinical features and treatment of scleroderma -- Inflammatory diseases of muscle and other myopathies -- Overlap syndromes -- Classification and epidemiology of systemic vasculitis -- Giant cell arteritis, polymyalgia rheumatica, and Takayasu's arteritis -- Anti-neutrophil cytoplasmic antibody--associated vasculitis -- Polyarteritis nodosa and related disorders -- Immune complex--mediated small-vessel vasculitis -- Primary angiitis of the central nervous system -- Beh�cet's disease -- Etiology and pathogenesis of hyperuricemia and gout -- Clinical features and treatment of gout -- Calcium crystal disease : calcium pyrophosphate dihydrate and basic calcium phosphate -- Familial autoinflammatory syndromes -- Pathogenesis of osteoarthritis -- Clinical features of osteoarthritis -- Treatment of osteoarthritis -- Metabolic bone disease -- Proliferative bone diseases -- Osteonecrosis -- Relapsing polychondritis -- Heritable diseases of connective tissue -- Etiology and pathogenesis of juvenile idiopathic arthritis -- Clinical features and treatment of juvenile idiopathic arthritis -- Pediatric systemic lupus erythematosus, juvenile dermatomyositis, scleroderma, and vasculitis -- Bacterial arthritis -- Lyme disease -- Mycobacterial infections of bones and joints -- Fungal infections of bones and joints -- Rheumatic manifestations of human immunodeficiency virus infection -- Viral arthritis -- Rheumatic fever and post-streptococcal arthritis -- Amyloidosis -- Sarcoidosis -- Hemochromatosis -- Hemophilic arthropathy -- Rheumatic manifestations of hemoglobinopathies -- IgG4 -related disease -- Arthritis accompanying endocrine and metabolic disorders -- Musculoskeletal syndromes in malignancy -- Tumors and tumor-like lesions of joints and related structures.
Summary: Consult the definitive resource in rheumatology for an in-depth understanding of scientific advances as they apply to clinical practice. Masterfully edited by Drs. Gary S. Firestein, Ralph C. Budd, Sherine E. Gabriel, Iain B. McInnes, and James R. O'Dell, and authored by internationally renowned scientists and clinicians in the field, Kelley and Firestein's Textbook of Rheumatology, 10th Edition, delivers the knowledge you need for accurate diagnoses and effective patient care. From basic science, immunology, anatomy, and physiology to diagnostic tests, procedures, and specific disease processes, this state-of-the-art reference provides a global, authoritative perspective on the manifestations, diagnosis and treatment of rheumatic diseases.
List(s) this item appears in: COM - Rheumatology
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Revised edition of: Kelley's textbook of rheumatology / Gary S. Firestein [and others]. 9th ed. c2013.

Includes bibliographical references and index.

Biology of the normal joint -- Synovium -- Cartilage and chondrocytes -- Biology, physiology, and morphology of bone -- Muscle : anatomy, physiology, and biochemistry -- Biomechanics -- Regenerative medicine and tissue engineering -- Proteinases and matrix degradation -- Dendritic cells : general overview and role in autoimmunity -- Mononuclear phagocytes -- Neutrophils -- T lymphocytes -- B cells -- Fibroblasts and fibroblast-like synoviocytes -- Mast cells -- Platelets -- Innate immunity -- Adaptive immunity and organization of lymphoid tissues -- Autoimmunity -- Metabolic regulation of immunity -- Genetics of rheumatic diseases -- Epigenetics of rheumatic diseases -- Complement system -- Prostaglandins, leukotrienes, and related compounds -- Cell recruitment and angiogenesis -- Cytokines -- Principles of signaling -- Immunologic repercussions of cell death -- Experimental models for rheumatoid arthritis -- Neuronal regulation of pain and inflammation -- Clinical research methods in rheumatic disease -- Economic burden of rheumatic diseases -- Assessment of health outcomes -- Biologic markers in clinical trials and clinical care -- Occupational and recreational musculoskeletal disorders -- Cardiovascular risk in inflammatory rheumatic disease -- Cancer risk in rheumatic diseases -- Introduction to physical medicine, physical therapy, and rehabilitation -- Pregnancy and rheumatic diseases -- History and physical examination of the musculoskeletal system -- Acute monoarthritis -- Evaluation and differential diagnosis of polyarthritis -- Skin and rheumatic diseases -- The eye and rheumatic diseases -- Neck pain -- Shoulder pain -- Low back pain -- Hip and knee pain -- Foot and ankle pain -- Hand and wrist pain -- Temporomandibular joint pain -- Fibromyalgia -- Synovial fluid analyses, synovial biopsy, and synovial pathology -- Arthrocentesis and injection of joints and soft tissue -- Anti-nuclear antibodies -- Autoantibodies in rheumatoid arthritis -- Acute phase reactants and the concept of inflammation -- Imaging in rheumatic diseases -- Biology and therapeutic targeting of prostanoids -- Glucocorticoid therapy -- Traditional dmards : methotrexate, leflunomide, sulfasalazine, hydroxychloroquine, and combination therapies -- Immunosuppressive drugs -- Anti-cytokine therapies -- Cell-targeted biologics and emerging targets : rituximab, abatacept, and other biologics -- Novel intra-cellular targeting agents in rheumatic disease -- Urate-lowering therapy -- Analgesic agents in rheumatic disease -- Nutrition and rheumatic diseases -- Etiology and pathogenesis of rheumatoid arthritis -- Clinical features of rheumatoid arthritis -- Treatment of rheumatoid arthritis -- Early synovitis and early undifferentiated arthritis -- Sj�ogren's syndrome -- Etiology and pathogenesis of spondyloarthritis -- Ankylosing spondylitis -- Undifferentiated spondyloarthritis -- Psoriatic arthritis -- Enteropathic arthritis -- Etiology and pathogenesis of systemic lupus erythematosus -- Clinical features of systemic lupus erythematosus -- Treatment of systemic lupus erythematosus --

Anti-phospholipid syndrome -- Etiology and pathogenesis of scleroderma -- Clinical features and treatment of scleroderma -- Inflammatory diseases of muscle and other myopathies -- Overlap syndromes -- Classification and epidemiology of systemic vasculitis -- Giant cell arteritis, polymyalgia rheumatica, and Takayasu's arteritis -- Anti-neutrophil cytoplasmic antibody--associated vasculitis -- Polyarteritis nodosa and related disorders -- Immune complex--mediated small-vessel vasculitis -- Primary angiitis of the central nervous system -- Beh�cet's disease -- Etiology and pathogenesis of hyperuricemia and gout -- Clinical features and treatment of gout -- Calcium crystal disease : calcium pyrophosphate dihydrate and basic calcium phosphate -- Familial autoinflammatory syndromes -- Pathogenesis of osteoarthritis -- Clinical features of osteoarthritis -- Treatment of osteoarthritis -- Metabolic bone disease -- Proliferative bone diseases -- Osteonecrosis -- Relapsing polychondritis -- Heritable diseases of connective tissue -- Etiology and pathogenesis of juvenile idiopathic arthritis -- Clinical features and treatment of juvenile idiopathic arthritis -- Pediatric systemic lupus erythematosus, juvenile dermatomyositis, scleroderma, and vasculitis -- Bacterial arthritis -- Lyme disease -- Mycobacterial infections of bones and joints -- Fungal infections of bones and joints -- Rheumatic manifestations of human immunodeficiency virus infection -- Viral arthritis -- Rheumatic fever and post-streptococcal arthritis -- Amyloidosis -- Sarcoidosis -- Hemochromatosis -- Hemophilic arthropathy -- Rheumatic manifestations of hemoglobinopathies -- IgG4 -related disease -- Arthritis accompanying endocrine and metabolic disorders -- Musculoskeletal syndromes in malignancy -- Tumors and tumor-like lesions of joints and related structures.

Online resource; title from pdf title page (ClinicalKey, viewed September 9, 2016).

Consult the definitive resource in rheumatology for an in-depth understanding of scientific advances as they apply to clinical practice. Masterfully edited by Drs. Gary S. Firestein, Ralph C. Budd, Sherine E. Gabriel, Iain B. McInnes, and James R. O'Dell, and authored by internationally renowned scientists and clinicians in the field, Kelley and Firestein's Textbook of Rheumatology, 10th Edition, delivers the knowledge you need for accurate diagnoses and effective patient care. From basic science, immunology, anatomy, and physiology to diagnostic tests, procedures, and specific disease processes, this state-of-the-art reference provides a global, authoritative perspective on the manifestations, diagnosis and treatment of rheumatic diseases.

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